Recently published: "Network Module-Based Model in the Differential Expression Analysis for RNA-seq". Bioinformatics. (2017, April). READ MORE >
Recently published: "CanProVar 2.0: An Updated Database of Human Cancer Proteome Variation". Journal of Proteome Research. (2017, Feb). READ MORE >
Recently published: "Construction and Deciphering of Human Phosphorylation-Mediated Signaling Transduction Networks".Journal of Proteome Research. (2015, Jul). READ MORE >
Recently published: "Network-Based Association Study of Obesity and Type 2 Diabetes with Gene Expression Profiles". Biomed Res Int. (2015, Jul). READ MORE >
Recently published: "Biological Network Module-Based Model for the Analysis of Differential Expression in Shotgun Proteomics". Journal of Proteome Research. (2014, Dec). READ MORE >
Recently published: "GroupRank: Rank Candidate Genes in PPI Network by Differentially Expressed Gene Groups". PLOS ONE. (2014, Oct). READ MORE >
We are interested in formulating the processes of complex phenotype/diseases (specifically in cancers) and prioritizing disease genes or variations by integrating interpretation of transcription and translation data using regulatory/ interaction network and public literatures. Our main focus is construction ofbiological network/pathway and modularity underneath specific molecular processes or biological states, identification of functional sub-network/module and optimization of statistic models and development of systems biology approaches for identifying individual and modular biomarker of complex disease from microarray transcriptional and shotgun proteomics data. Selected papers:
Biostatistics& Bioinformatics Workshop 2017
[April] Welcome new PhD student Yafei Chang to our lab.
[April] Mingli's statistical model paper is accepted to Bioinformatics.
[March] Xiaojing's allergen prediction paper is online at Interdisciplinary Sciences: Computational Life Sciences
[Feb] Menghuan's CanProVar 2.0 paper is published at Journal of Proteome Research.
[Sep] Wecome Xi Cheng and Jingya Jia to our group.
[May] Congratulations to Jing Li, and Xi Cheng for receiving the University's Outstanding Graduate.
[Sept] Master students Jinqiu Xiao joined the group. Welcome!
[Sept] Welcome new PhD student Peng Cui to our lab.
[July] Menghuan Zhang's paper is published at Journal of Proteome Research.
[Feb] Siyi Zhang's paper is accepted to BioMed Research International.
Room 221, Building 4, Biology Complex 800 Dongchuan Road, Minhang District Shanghai, China, 200240